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Technology Information

Title	New Flow Controller and Impactor Technology for Liquid Chromatography Detectors
Case Number	08UMS012
Manager	Tamara Wilgers ( wilgerst@umsl.edu )
Abstract	Novel Technology to Eliminate Jagged Peak Noise, Reduce Baseline Noise, and Greatly Increase Sensitivity in Liquid Chromatography Detectors Inventor: Dr. Zhi Xu, Department of Chemistry, University of Missouri-St. Louis Evaporative light scattering detectors (ELSDs), charged aerosol detectors (CADs), and mass spectrometers are used routinely as Liquid Chromatography (LC) detectors for the analysis of a wide variety of chemical and biochemical samples. However, these detection devices suffer from various drawbacks, including relatively high levels of jagged peak noise, as shown by Figure 1 (see downloadable PDF). Such excessive jagged peak noise can hamper the ability of the detection device to accurately determine the sample properties and can decrease sensitivity overall. Researchers at UM-St. Louis have developed a new flow controller technology for liquid chromatography detectors. The flow controller technology eliminates the jagged peak noise of conventional detection methodologies and significantly reduces the baseline noise for all three detectors mentioned above. The effect of the technology is shown in Figure 2 (see downloadable PDF). APPLICATIONS > Detectors used for Liquid Chromatography analysis including ELSDs, CADs and mass spectrometers. BENEFITS > Eliminates jagged peak noise common in liquid chromatography detectors (ELSDs, CADs, mass spectrometers). > Reduces baseline noise in LC detectors. > Increases the Signal-to-Noise ratio of LC detectors. > Technology is easily and inexpensively retrofitted to work on existing or designed into new LC detectors. IP STATUS: > U.S. Provisional Application filed (priority date 6/11/08) CONTACT To discuss this opportunity, please contact: Tamara Wilgers Director of Technology Transfer University of Missouri-St. Louis 314-516-6884 wilgerst@umsl.edu UMSL REFERENCE #08UMS012
Taxonomy	Technology Categories/Analysis and Detection/Chemical Technology Categories/Detection/Research Tools Technology Categories/Test and Measurement/Research Tools Technology Categories/Chromatography/Research Tools
Keywords	UM-St. Louis, noise cancellation, signal-to-noise ratio, chemical sample analysis, analysis, chemical, evaporative light scattering detector (ELSD), liquid chromatography, analytical instruments, ELSD, umsl, charged aerosol detectors (CAD), mass spectrometer, biochemical sample analysis, biochemical, jagged peak noise, baseline noise

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Name	Size	Description	Download
business-opportunity_08UMS012.pdf	447772	Document Type: pdf Submitted by user: wilgerst Submitted on: 05/27/2009, 10:13:36 Business opportunity, technology summary 08UMS012	Download

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